Journal article
bioRxiv, 2023
APA
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Mongrédien, R., Anésio, A., Fernandes, G. J. D., Eagle, A., Maldera, S., Pham, C., … Vialou, V. (2023). Astrocytes control cocaine-induced synaptic plasticity and reward through the matricellular protein hevin. BioRxiv.
Chicago/Turabian
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Mongrédien, R., Augusto Anésio, G.J.D. Fernandes, A. Eagle, Steeve Maldera, Cuong Pham, Adèle Vilette, et al. “Astrocytes Control Cocaine-Induced Synaptic Plasticity and Reward through the Matricellular Protein Hevin.” bioRxiv (2023).
MLA
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Mongrédien, R., et al. “Astrocytes Control Cocaine-Induced Synaptic Plasticity and Reward through the Matricellular Protein Hevin.” BioRxiv, 2023.
BibTeX Click to copy
@article{r2023a,
title = {Astrocytes control cocaine-induced synaptic plasticity and reward through the matricellular protein hevin},
year = {2023},
journal = {bioRxiv},
author = {Mongrédien, R. and Anésio, Augusto and Fernandes, G.J.D. and Eagle, A. and Maldera, Steeve and Pham, Cuong and Vilette, Adèle and Bianchi, P. and Franco, Clara and Louis, F. and Gruszczynski, C. and Betancur, Catalina and Erdozain, A. M. and Robison, A. J. and Boucard, A. and Li, Dongdong and Cruz, F. and Gautron, S. and Heck, N. and Vialou, V.}
}
Drug addiction involves profound modifications of neuronal plasticity in the nucleus accumbens, which may engage various cell types. Here, we report prominent effects of cocaine on calcium signals in astrocytes characterized by in vivo fiber photometry. Astrocyte calcium signals in the nucleus accumbens are sufficient and necessary for the acquisition of cocaine seeking behavior. We identify the astrocyte-secreted matricellular protein hevin as an effector of the action of cocaine and calcium signals on reward and neuronal plasticity.